Progress report on EGTA and OSR measurement in retina

Kevin Sean Chen — Sat, 02 May 2015 07:01:46 +0000

During the last two months, we started adding EGTA, a calcium chelator in the buffer and observed change in OSR. Surprisingly, period doubling occurred at some specific concentration, and didn’t abolish OSR. We think that EGTA affects the time scale in the whole retina activity.

Following up, we designed light stimuli with two periods and also produced activity similar to period doubling, then measured the latency of OSR. In fact, the latency seems to be highly dependent to the last pulse. We can control the latency through the brightness of the last pulse. This may be a useful method for our future work, to do real-time feedbacks on retina for latency control.

Tags:

retina

EGTA

period doubling

OSR

group meeting

Laboratory of Computing Biological Networks - EGTA

Progress report on EGTA and OSR measurement in retina