Author: chunchung

Theoretical and computational physicist with interest in biological networks

Web: networks.tir.tw

Kai-Yi Wang, Jei-Wei Wu, Jen-Kun Cheng, Chun-Chung Chen, Wai-Yi Wong, Robert G. Averkin, Gábor Tamás, Kazu Nakazawa, Cheng-Chang Lien Cell Reports 36, no. 11 (2021) https://doi.org/10.1016/j.celrep.2021.109702 Modulation of hippocampal dentate gyrus (DG) excitability regulates anxiety. In the DG, glutamatergic mossy cells (MCs) receive the excitatory drive from principal granule cells (GCs) and mediate the feedback…

Read More Elevation of hilar mossy cell activity suppresses hippocampal excitability and avoidance behavior

Yi-Ling Chen, Chun-Chung Chen, Yu-Ying Mei, Ning Zhou, Dongchuan Wu, Ting-Kuo Lee https://arxiv.org/abs/2102.13300 Using miniscope recordings of calcium fluorescence signals in the CA1 region of the hippocampus of mice, we monitor the neural activity of hippocampal regions while the animals are freely moving in an open chamber. Using a data-driven statistical modeling approach, the statistical…

Read More Ubiquitous proximity to a critical state for collective neural activity in the CA1 region of freely moving mice

Ravi Kumar, Yu-Ting Huang, Chun-Chung Chen, Shun-Fen Tzeng, and Chi-Keung ChanCerebral Cortex Communications 1 (1): tgaa053 (2020). https://doi.org/10.1093/texcom/tgaa053. Synchronous bursting (SB) is ubiquitous in neuronal networks and independent of network structure. Although it is known to be driven by glutamatergic neurotransmissions, its underlying mechanism remains unclear. Recent studies show that local glutamate recycle by astrocytes…

Read More Astrocytic Regulation of Synchronous Bursting in Cortical Cultures: From Local to Global