group meeting

Notes on group meetings.

Spatiotemporal Memory Is an Intrinsic Property of Networks of Dissociated Cortical Neurons

Following Tina's presentation last time, this article was published by the same group this year and they moved on to investigate spatiotemporal memory properties in the cultured neural network. I think some ideas and results in the article may be informative for the work on retina and the future works in cultured neurons in our group.

Simulation of spontaneous bursting activities

The spontaneous bursting activities can be widely observed in many different experiments about the development of neuronal networks. One typical example is the periodical spontaneous bursting activity during development of the in-vitro cortical neuronal network from embryonic rat's brains observed through the MEA device. Currently, I am working on the simulation of this type of neuronal activities and, based on our simulations, try to understand the generation mechanism of what we have observed from experiments.

Single Action Potentials and Subthreshold Electrical Events Imaged in Neurons with a Fluorescent Protein Voltage Probe

Paper site

A genetically encoded sensor of membrane potential, FlaSh, was first introduced by Siegel and Isacoff (1997) as a fusion between the Shaker potassium channel and wild-type green fluorescent protein from Aequorea victoria (aqGFP).

Subsequent ion channel-based voltage sensors were designed to include a single fluorescent protein or FPs that form Förster Resonance Energy Transfer pairs (FRET).

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